Randomized Comparative Bioavailability of a Novel 3D Printed Fast Melt Formulation of Levetiracetam Following the Administration of a Single 1000 mg Dose to Healthy Human Volunteers under Fasting and Fed Conditions
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Randomized Comparative Bioavailability of a Novel Three-Dimensional Printed Fast-Melt Formulation of Levetiracetam Following the Administration of a Single 1000-mg Dose to Healthy Human Volunteers Under Fasting and Fed Conditions
BACKGROUND Rapidly disintegrating or 'fast-melt' oral formulations have been developed recently to facilitate drug intake among patients. Even though these formulations have helped to improve therapy adherence, some of their limitations include: the dissolution time, their facility to be swallowed, and the dosage strengths that may be accommodated. To overcome these limitations, a novel, porous...
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